2011-2014

168 Short and efficient syntheses of protoberberine alkaloids using palladium catalyzed enolate arylation

Alice E. Gatland, Ben S. Pilgrim, Panayiotis A. Procopiou and Timothy J. Donohoe

Angewandte Chemie Int. Ed., 2014, 53, 14555-14558.

DOI: 10.1002/anie.201409164

167 Love-Hate ligands for high resolution analysis of strain in ultra-stable protein:small molecule interaction

Michael Fairhead, Di Shen, Louis K. M. Chan, Ed D. Lowe, Timothy J. Donohoe, Mark Howarth

Bioorganic & Medicinal Chemistry, 2014, 22, 5476-5486.

DOI: 10.1016/j.bmc.2014.07.029

166 New methods for the synthesis of naphthyl amines; application to the synthesis of dihydrosanguinarine, sanguinarine, oxysanguinarine and (±)-maclekarpines B and C

Matthew R. Tatton, Iain Simpson and Timothy J. Donohoe

Chem. Commun., 2014, 50, 11314-11316.

DOI: 10.1039/C4CC05209A

165 De novo Synthesis of Multi-Substituted Aryl Amines using Alkene Cross Metathesis

Matthew Tatton, Iain Simpson and Timothy J. Donohoe

Organic Letters, 2014, 16, 1920-1923.

DOI: 10.1021/ol500441q

164 Rhodium-Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of Alpha-Branched Products

Louis K. M. Chan, Darren L. Poole, Di Shen, Mark P. Healy and Timothy J. Donohoe

Angewandte Chemie Int. Ed., 2014, 53, 761-765. Designated as a HOT paper, featured as the back cover.

DOI: 10.1002/anie.201307950

163 Total Synthesis of the Antitumor Antibiotic (+/-)-Streptonigrin: First and Second Generation Routes for de-novo Pyridine Formation using Ring Closing Metathesis

Timothy Donohoe, Christopher Jones, Anne Kornahrens, Luiz Barbosa, Louise Walport, Matthew Tatton, Michael O'Hagan, Akshat Rathi, David Baker

J. Org. Chem. 2013, 78, 12338-12350. Selected as a Featured Article.

DOI: 10.1021/jo402388f

162 Modular isoquinoline synthesis using catalytic enolate arylation and in-situ functionalization

Ben Pilgrim, Alice Gatland, Charlie McTernan, Panayiotis Procopiou, Timothy Donohoe

Organic Letters, 2013, 15, 6190-6193.

DOI: 10.1021/ol4030309

161 Tethered Aminohydroxylation: Synthesis of the β-Amino Acid of Microsclerodermins A and B

Robert D. C. Pullin , Akshat H. Rathi, Ekaterina Y. Melikhova, Christian Winter , Amber L. Thompson, and Timothy J. Donohoe

Org. Lett. 2013, 15, 5492-5495.

DOI: 10.1021/ol402638n

160 Lithium-4,4'-Di-tert-butylbiphenylide

Christopher R. Jones and Timothy J. Donohoe

Encyclopedia of Reagents for Organic Synthesis, 2013.

159 Vinyl Weinreb Amides: A Versatile Alternative to Vinyl Ketone Substrates for Heck Arylation

David B. Baker, Peter T. Gallagher and Timothy J. Donohoe

Tetrahedron 2013, 69, 3690-3697.

DOI: 10.1016/j.tet.2013.03.009

158 Osmium-Catalyzed Oxidative Cyclization of Dienes and Their Derivatives

Ben S. Pilgrim and Timothy J. Donohoe

J. Org. Chem. 2013, 78, 2149-2167. Work from this paper featured in the cover picture for JOC.

DOI: 10.1021/jo302719y

157 Interplay of cascade oxidative cyclisation and hydride shifts in the synthesis of the ABC spiroketal ring system of pectenotoxin-4

Timothy, J. Donohoe and Radek Lipinski

Angew. Chem. Int. Ed. 2013, 52, 2491-2494. Designated as a Hot Article.

DOI: 10.1002/anie.201208919

156 Oxidative cyclisation for the synthesis of complex THF-containing natural products

Timothy, J. Donohoe, Robert D. C. Pullin, Radoslaw M. Lipinski

Pure & Applied Chem. 2013, 85, 1175-1184.

DOI: 10.1351/PAC-CON-12-10-25

155 Partial and complete reduction of pyrroles, furans, thiophenes and their benzo-analogues and of aromatic heterocycles containing more than one heteroatom

Timothy J. Donohoe, Christopher Jones and Christian Winter

Comprehensive Organic Synthesis II, Ed. G. Molander and P. Knochel, Elsevier, 2013.

154 Asymmetric Synthesis of the Fully Elaborated Pyrrolidone Core of Oxazolomycin A

Timothy J. Donohoe, Timothy J. C. O'Riordan, Manuel Peifer, Christopher R. Jones, Timothy J. Miles

Organic Lett. 2012, 14, 5460-5463.

DOI: 10.1021/ol302541j

153 Natural Product Synthesis as a Challenging Test of Newly Developed Methodology

Timothy J. Donohoe, Robert D. C. Pullin

Chemical Commun. 2012, 48, 11924-11938.

DOI: 10.1039/C2CC36040C

152 Synthesis of substituted isoquinolines utilizing palladium-catalyzed α-arylation of ketones

Timothy J. Donohoe, Ben S. Pilgrim, Geraint R. Jones and José A. Bassuto

Proc. Natl. Acad. Sci. US, 2012, 109, 11605-11608.

DOI: 10.1073/pnas.1206532109

151 A green approach to Fenton chemistry: Hydroxylation of salicylic acid in aqueous medium using electrogeneration of Fenton's Reagent

Janjira Panchompoo, Leigh Aldous, Mikhail Kabeshov, Ben S. Pilgrim, Timothy J. Donohoe and Richard G. Compton

New. J. Chem. 2012, 36, 1265-1272.

DOI: 10.1039/C2NJ21007J

150 Hydrogen-Bonding-Mediated Directed Osmium Dihydroxylation

Timothy J. Donohoe, Carole J. R. Bataille, Paolo Innocenti

Organic Reactions, 2012, 76, 1-47.

DOI: 10.1002/0471264180.or076.01

149 Olefin Cross-Metathesis for the Synthesis of Heteroaromatic Compounds

Timothy J. Donohoe, John F. Bower and Louis K. M. Chan

Org. Biomol. Chem. 2012, 10, 1322-1328. Designated as a Hot Article.

DOI: 10.1039/C2OB06659A

148 Improvements in the Tethered Aminohydroxylation Reaction and its Application to Total Synthesis

Timothy J. Donohoe, Cedric K. A. Callens, Adam R. Lacy, Christian Winter

Eur. J. Org. Chem. 2012, 4, 655-663 (plus cover picture for this issue).

DOI: 10.1002/ejoc.201101464

147 Direct Preparation of thiazoles, imidazoles, imidazopyridines and thiazolidines from alkenes

Timothy J. Donohoe, Mikhail Kabeshov, Akshat Rathi and Ian E. D. Smith

Org. Biomol. Chem. 2012, 10, 1093-1101.

DOI: 10.1039/C1OB06587D

146 Tethered aminohydroxylation

Timothy J. Donohoe and Stefanie Mesch

Asymmetric Synthesis – The Essentials II. Edited by Mathias Christmann and Stefan Brase, WILEY-VCH, 2012, 17-26.

145 Amino acid based reoxidants for aminohydroxylation: application to the construction of amino acid-aminoalcohol conjugates

Timothy J. Donohoe, Cedric K. A. Callens, Aida Flores, Stefanie Mesch, Darren L. Poole and Ishmael A. Roslan

Angew. Chem. Int. Ed. 2011, 50, 10957-10960.

DOI: 10.1002/anie.201103293

144 Synthesis of 2,4,6-Trisubstituted Pyridines via an Olefin Cross-Metathesis/Heck-Cyclisation-Elimination Sequence

Timothy J. Donohoe, John F. Bower, David B. Baker, José A. Basutto, Louis K. M. Chan and Peter Gallagher

Chemical Commun. 2011, 47, 10611-10613.

DOI: 10.1039/C1CC14257G

143 Total synthesis of (±)-streptonigrin: de novo construction of a pentasubstituted pyridine using ring-closing metathesis

Timothy J. Donohoe, Christopher R. Jones, and Luiz C. A. Barbosa

J. Am. Chem. Soc. 2011, 133, 16418–16421.

DOI: 10.1021/ja207835w

142 Surface plasmon resonance imaging of glycoarrays identifies novel and unnatural carbohydrate-based ligands for potential ricin sensor development

Margherita Fais, Rositsa Karamanska, Sarah Allman, Shirley A. Fairhurst, Paolo Innocenti, Antony J. Fairbanks, Timothy J. Donohoe, Benjamin G. Davis, David A. Russell and Robert A. Field

Chemical Science, 2011, 2, 1952-1959.
DOI: 10.1039/C1SC00120E

141 The Influence of Exocyclic Stereochemistry on the Tethered Aminohydroxylation Reaction

Timothy J. Donohoe, Adam R. Lacy, Akshat H. Rathi, and Daryl S. Walter

Chemistry: An Asian Journal, 2011, 6, 3214-3222.
DOI: 10.1002/asia.201100497

140 A short and efficient synthesis of neodysiherbaine A using catalytic oxidative cyclisation

Timothy J. Donohoe, Paul Winship, Matthew R. Tatton and Peter Szeto

Angew. Chem. Int. Ed. 2011, 50, 7604-7606.
DOI: 10.1002/anie.201102525

139 Dehydrogenation of Cyclic-Thioethers Bound to a [Rh(diphosphine)]+ Fragment

Romeao Dallanegra, Ben S. Pilgrim, Adrian B. Chaplin, Timothy J. Donohoe and Andrew S. Weller

Dalton Transactions, 2011, 40, 6626-6628.
DOI: 10.1039/C1DT10503E

138 Exerting Control over the Acyloin Reaction

Timothy J. Donohoe, Ali Jahanshahi, Michael J. Tucker, Farrah L. Bhatti, Ishmael A. Roslan, Mikhail Kabeshov and Gail Wrigley

Chemical Commun. 2011, 47, 5849-5851.
DOI: 10.1039/C1CC11654A

137 Intramolecular Hydride Addition to Pyridinium Salts: New Routes to Enantiopure Dihydropyridones

Timothy J. Donohoe, Matthew J. Connolly, Akshat H. Rathi and Lesley Walton

Organic Lett. 2011, 13, 2074-2077.
DOI: 10.1021/ol200478p

136 Palladium nanoparticle-modified carbon nanotubes for electrochemical hydrogenolysis in ionic liquids

Yao Meng, Leigh Aldous, Ben S. Pilgrim, Timothy J. Donohoe and Richard G. Compton

New Journal of Chemistry, 2011, 35, 1369-1375.
DOI: 10.1039/C1NJ20070D

135 Heteroaromatic Synthesis via Olefin Cross-Metathesis: Entry to Polysubstituted Pyridines

Timothy J. Donohoe, José Basutto, Akshat H. Rathi and John F. Bower

Organic Lett. 2011, 13, 1036-1039.
DOI: 10.1021/ol103088r

134 Recent Developments in Methodology for the Direct Oxyamination of Olefins

Timothy J. Donohoe, Aida Flores, Cedric K.A. Callens, Adam J. Lacy, Akshat H. Rathi

Chem. Eur. J., 2011, 17, 58-76.
DOI: 10.1002/chem.201002323

133 Osmium-free direct syn-dihydroxylation of alkenes

Carole J. R. Bataille and Timothy J. Donohoe

Chem. Soc. Rev. 2011, 40, 114-128.
DOI: 10.1039/B923880H